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They dont overlap much

Diarrhea, vomiting, and reduced intake can increase the risk of dehydration

Evidence base GLP-1 medications have extensive randomised controlled trial data demonstrating cardiovascular and renal benefits in addition to glycaemic control

The warning signs include: Severe, worsening abdominal pain that does not resolve Vomiting undigested food many hours after eating (4+ hours) Complete inability to keep food down for more than 24 hours Feeling full after just a few bites consistently across multiple days Visible, persistent abdominal distension that does not fluctuate Unintentional weight loss beyond what is expected from the medication Inability to pass gas or have bowel movements for 3+ days If you experience these symptoms, stop taking semaglutide and contact your healthcare provider immediately

See: "Mercaptanet, med bemaerkninger over nogle andre nye producter af svovelvinsyresaltene, som og af den tunge vinolie, ved sulfureter" [Mercaptan, with remarks on some other new products of salts of ethyl hydrogen sulfate as well as of heavy oil of wine, by means of hydrogen sulfide]