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Amazon One Medical (cash pay): Oral GLP-1 (Foundayo, oral Wegovy): $149/month Injectable GLP-1 (Wegovy, Zepbound): $299/month New patient consultation: billed separately per visit On-demand renewal (message): $29 per request On-demand renewal (video): $49 per request One Medical membership (optional): $199/year Direct Meds (cash pay): Compounded semaglutide: below Amazon's injectable floor Consultation included within program structure No membership fees No per-renewal charges during active treatment The bottom line for cash-pay patients: Direct Meds delivers a lower total monthly cost for patients seeking injectable compounded semaglutide with consultation costs built into the program rather than stacked on top of medication costs

FDA Regulatory Notice: As of March 2026, the FDA has escalated enforcement against non-FDA-approved compounded GLP-1 products, including issuing 30 warning letters to telehealth companies on March 3, 2026