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clinical trials of agents like liraglutide have shown cognitive improvements in patients with early Alzheimers disease

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Carnitine has a protective effect on glaucoma-induced retinal ganglion cells injury by reducing the expression of typical markers of cell stress, such as glial fibrillary acidic protein (GFAP), inducible nitric oxide synthase (iNOS), ubiquitin and caspase-3, and reducing the level of the lipid peroxidation product malondialdehyde (MDA) [318]

Moreover, skin can look slightly pale/dull over time