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While we are hard-wired for stories as humans (which is why anecdotes are so compelling!), it turns out a random spattering of stories is often not enough information

Effect of position on intracranial pressure and compliance: a cross-sectional study including 101 patients

While some of these benefits come indirectly via weight loss, GLP-1s seem to also directly impact different organs by reducing inflammation or via other biological pathways

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But these types of activities that encourage pushing yourself to the limit (combined with other types of stress) can lead to problematic chronic inflammation