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GLP-1 receptor agonists in heart failure GLP-1 receptor agonists have demonstrated favorable cardiovascular effects in patients with T2DM and obesity as meta-analyses suggest a reduction in hospitalization for incident or new-onset HF of approximately 18%, alongside reductions in major adverse cardiovascular events [6, 14, 15]

Their filing for FDA approval of CagriSema in early 2026 puts them on track for a potential approval decision by late 2026 or early 2027

Its increased metabolism results in the breakdown and elimination of fat from the body occurring at a faster rate

J Physiol Pharmacol 60(Suppl 7):191196 Callahan CM, Apostolova LG, Gao S, Risacher SL, Case J, Saykin AJ, Lane KA, Swinford CG, Yoder MC (2020) Novel markers of angiogenesis in the setting of cognitive impairment and dementia

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