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The data also indicate that pyridoxine supplementation only reduces the hyperhomocysteinemia detected after oral methionine administration in vitamin B 6 -deficient patients or in heterozygotes for CBS deficiency

The disc issue is still there on imaging

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Nle-AngIV also increased spine numbers to 32 spines/50m, but to a lesser extent than Dihexa

And freezing, while it preserves the unreconstituted powder, destroys the reconstituted solution by forming ice crystals that shear peptide molecules apart