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If the up- or down-regulation of CAC causes an increase or decrease of mitochondrial carnitine remains to be established
The primary contenders are valproic acid, fosphenytoin, or lacosamide
Presence, activity and properties of glutaredoxins are often analysed in coupled spectrophotometric reductive assays with bis(2-hydroxyethyl)disulfide (HEDS) as a non-glutathione substrate 10,11,12,15,16,17,18 or L-cysteine-glutathione disulfide (GSSCys) as a glutathionylated substrate 10,11,12,18,19,20,21 (Fig
Compared to other well-known antioxidants like vitamin C and vitamin E, glutathione stands out for its comprehensive cellular protection
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