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Nitro fatty acids Nitro-fatty acids (NO 2 -FAs) are endogenous signalling mediators with strong anti-fibrotic and anti-inflammatory activities [286], able to promote NRF2 activation through the interaction and reversible post-translational modification of C273 and C288 present in the stress sensing domain (IVR) of KEAP1 [287]
Effects of semaglutide on risk of cardiovascular events across a continuum of cardiovascular risk: combined post hoc analysis of the SUSTAIN and PIONEER trials
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