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Circulation 2008;117:2340-50.ArticlePubMed 24

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DPP-4 is an integral membrane protein which has a widespread distribution, being expressed in numerous tissues including intestinal and renal brush border membranes, vascular endothelium, the liver and pancreas, glandular epithelial cells, and by cells of the immune system (where it is also known as the T-cell differentiation antigen, CD26)

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In that scenario, three 10 mg vials over twelve weeks costs more per milligram but wastes nothing

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Called orthostatic hypotension, this happens when blood pressure drops too quickly on standing

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