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While medications such as GLP-1 receptor agonists (Ozempic, Wegovy) and SGLT-2 inhibitors (Jardiance, Farxiga) demonstrated powerful benefits, they quickly were determined to pose too much of a liability for pharmaceutical companies or regulators due to concerns about safety

Zhang N, Gao M, Hu X, Wang P, Cheng Y, Wei H, Fu G, Ge J, Li H, Zhang W, Zhou B

Acta Pharmacol Sin (2021) 43(5):115666

over 70).[ref] Supplemental L-carnitine: L-carnitine and acetyl-L-carnitine are readily available as supplements and may be beneficial for someone with carnitine-related genetic variants