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Iron represents an essential trace element in human physiology, participating in crucial processes including hemoglobin synthesis, oxygen transport, and diverse enzymatic reactions
In contrast, our study confirmed decreased glutathione levels and increased ROS levels through BSO treatment or GCLC silencing, and revealed that while the depletion of glutathione did not compromise lymphoma cell survival in 2D culture, it sharply diminished viability in 3D gels
In this study, we designed a peptide inhibitor based on the p53 transactivation domain (TAD) sequence and investigated its binding interface at the atomic level using NMR spectroscopy
C.CousinsD.SchectmanJ
One such piece of research is a 2020 review published in the journal Nutrients (1)
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