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The titration is simpler: start at 0.6 mg daily for one week, then increase to 1.2 mg, with an optional increase to 1.8 mg if additional glycemic control is needed
NICE recommends semaglutide (Wegovy) only through specialist tier 3/4 weight management services for adults with BMI 35 kg/m (or 32.5 kg/m for certain ethnic groups) plus at least one weight-related comorbidity, and only after intensive lifestyle intervention has been tried
Journal Reference : Sean Wharton, Paula Freitas, Jran Hjelmesth, Maria Kabisch, Kristian Kandler, Ildiko Lingvay, Maria Quiroga, Julio Rosenstock, W Timothy Garvey
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These weight loss medications often cause temporary side effects when treatment commences, which typically reduce within several weeks or months of use
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