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Other companies have active efforts in this space such as efinopegdutide (MK-6024) (51), pemvidutide (Altimmune, ALT-801) and mazdutide (LY3305677, IBI362, 52)

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In ARDS, neutrophils are actively involved in the inflammatory response and produce high levels of ROS through their NOX activity ( The mechanism of oxidative stress in ARDS The impact of oxidative stress on ARDS is mainly characterized by its role in worsening the damage to the alveolar-capillary barrier, provoking inflammatory responses, and resulting in cell death, which collectively contribute to the initiation and evolution of ARDS

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