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For patients planning pregnancy, semaglutide should be discontinued at least 2 months before a planned pregnancy due to the long half-life, while tirzepatide may persist for approximately 1 month
The patients recruited in this study were of older as compared to previous studies, which may have contributed to the variable results
Unlike traditional oral solid dosage products, oral GLP-1s require a distinct set of capabilities spanning advanced formulation and delivery science, specialised oral manufacturing for biologics, robust scale-up and lifecycle management, and resilient, high-quality supply chains
Other drugs are available that work similarly to semaglutide
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