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LiHWangYGuoJZhangPXuZPengKet al
Patients with elevated fasting insulin, insulin resistance (HOMA-IR above 2.5), or inflammatory markers like elevated hsCRP may show different GLP-1 response patterns than those with preserved insulin sensitivity
The primary endpoints that track response to MOTS-c therapy align with the peptide's core mechanisms: insulin sensitivity, mitochondrial function, body composition, and inflammatory tone
37 Small molecule GLP-1RAs are chemically synthesized, and compared to protein-based drugs, they generally have smaller molecular sizes
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