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Using germ-free mice, microbial perturbation, faecal microbiota transplantation and multiomic profiling, we show that metronidazole remodels the gut microbial ecology and reprograms Kupffer cells into a reduced-uptake state, thereby suppressing hepatic clearance and enhancing the tumour accumulation of nanomedicines across multiple formulations and tumour models
Chinese Society of Hepatology
2009 MayJun
Guan J, Krishnamurthi R, Waldvogel HJ, Faull RL, Clark R, Gluckman P
Most current data on the success of lipotropic injections comes from anecdotal evidence
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