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Oliaks bariatric surgery practice, now in functional wellness at MDTW
Berberine also inhibits dipeptidyl peptidase-4 (DPP-4), which degrades endogenous GLP-1
Occasional tingling or numbness in extremities (paresthesia)
In terms of tolerability, GLP-1RAs are commonly associated with GI side effects, which are often dose-dependent and time-limiting [55]
longum A 2025 randomized, double-blind, placebo-controlled trial reported that a Bifidobacterium breve strain significantly raised GLP-1 and fecal butyrate while improving insulin resistance in adults with obesity
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