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Acute administration effects suggest alternative metabolic mechanisms involving direct effects on cellular oxidative capacity

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Second, the lack of characterized liver tests/ultrasonography in the patient population precludes the evaluation of obesity-related liver complications

While Semaglutide (Ozempic/Wegovy) targets only GLP-1 receptors and Tirzepatide (Mounjaro/Zepbound) targets GLP-1 and GIP receptors, Retatrutide goes further by also engaging glucagon receptors

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