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Researchers new to the area often start with the foundational trials cited above before designing their own combination protocols

A diagnosis of the condition may be arrived at by visually examining the macules Dermoscopy: Dermoscopy is a diagnostic tool where a dermatologist examines the skin using a special magnified lens A tissue biopsy of the lesion is typically performed to confirm the diagnosis, and most importantly, to help rule out more serious conditions, such as melanoma, a type of skin cancer

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Induction of eryptosis in red blood cells using a calcium ionophore