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Examples Acarbose (Precose) Dosage Initial: 25 mg three times daily with first bite of each meal Maximum: Generally 300 mg, with meals, per day Miglitol (Glyset) Dosage Initial: 25 mg three times daily at the start of each meal Maximum: 50 mg three times daily Possible side effects include: Gastrointestinal: flatulence (gas), abdominal discomfort, diarrhea High-carbohydrate diet may worsen these side effects Gastrointestinal side effects usually become less pronounced with continued use Liver enzyme (transaminases) elevation Sulfonylureas Primary mechanism(s) of action Sulfonylureas stimulate insulin release by pancreatic beta cells
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A clinical study using a 0.2% low-molecular weight HA gel showed improvement in facial seborrheic dermatitis with excellent tolerance
Tirzepatide dual GIP/GLP-1 mechanism produces greater average weight loss (22.5% vs 15% to 17% for semaglutide in comparable trials) but also tends to cause more gastrointestinal side effects, particularly at higher doses
These drugs are injected once a month or infused intravenously once every three months
