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Some of the most studied nutrient abnormalities related to the long-term use of PPIs are hypomagnesemia, hypocalcemia, vitamin B12 deficiency, and hypo/hyperkalemia (Heidelbaugh 2013)
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Many of the claims circulating online remain largely theoretical
180 In an observational study that included 1,290 North American women, higher intake of omega-3 fatty acids from fish was correlated with shorter time to pregnancy, while higher intake of trans fatty acids was linked to lower pregnancy rates 181
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