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Retatrutide monotherapy achieved 24.2% weight reduction in phase 2 trials, while cagrilintide combined with semaglutide (CagriSema) reached 22.7%

Qsymia contains phentermine, so it works the same way, but it also contains the active ingredient topiramate, which is thought to work by suppressing appetite and increasing feelings of fullness

Next, SA--Gal staining was performed to monitor SIPS induction

However, they are dose-dependent