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Vitamin B12 deficiency causes many skin conditions like hyperpigmentation, acne, eczema, psoriasis, vitiligo and can lead to hair problems

Consult with a qualified healthcare provider before starting any peptide protocol

[9] [2] According to NICE guidance, patients with confirmed B12 deficiency and neurological involvement typically require more frequent initial dosing (alternate-day injections) until symptom improvement occurs

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And the metabolic effects observed in the diabetes trials have opened a new research direction connecting IRR activation to metabolic health an area that intersects with the broader metabolic peptide landscape including compounds like retatrutide and MOTS-C that approach metabolic regulation through entirely different receptor systems