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Initially, B12 shots are usually administered 1-3 times per week
Lachowicz-Scroggins ME, Yuan S, Kerr SC, Dunican EM, Yu M, Carrington SD, Fahy JV
For a topical application, the peptide never reaches the bloodstream at meaningful concentrations under most real-world conditions
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10.1038/s41418-017-0053-8 48
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