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Genetic factors, baseline body weight, lifestyle habits, and adherence influence outcomes
One case in the literature reports improvement in the clinical appearance and epidermal insulin signaling of AN in a 42-year-old woman with obesity and T2DM
Lilly is also leading this charge with retatrutide , a triple hormone receptor agonist that cut body weight by 26.6% on a placebo-adjusted basis at 68 weeks
The list of potential side effects is provided in Table 2
A small observational study published in JCI Insight (2022) examined individuals with obesity receiving semaglutide who reported reductions in alcohol intake, though the relationship to weight loss requires further investigation in controlled trials
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