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If the vitamin B12 is ingested in its protein bound form, then it must first undergo a proteolytic cleavage in the stomach or duodenum where it will bind to an R-binder and then enter into the duodenum for further cleavage.1,2,8 This proteolytic cleavage is mostly dependent on the functional activity of pepsin
Mixing : Rotate the vial in the hand in a circle
Their skin simply adjusts without incident
Ferrer-Vaquer et al., 2010
Summary More efficient oral and injectable forms may cause B12 overload
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