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Common side effects shared by both medications: Nausea (most common, usually transient peaks during dose escalation) Vomiting Diarrhea or constipation Decreased appetite and early satiety Bloating or stomach discomfort Injection site reactions Key safety warnings that apply to both drugs: FDA Boxed Warning (both): Possible risk of thyroid C-cell tumors, based on animal studies

Other patients may take a few days or weeks before noticing a significant difference

Consequently, particles with aerodynamic diameters between 1 m and 5 m are generally preferred for inhaled drug delivery 130

Improvements appeared in lipid profiles, insulin sensitivity markers, and aminotransferase levels in subjects with elevated baselines