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Keap1/nrf2 signaling: A new player in thyroid pathophysiology and thyroid cancer

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The first one is synthesized through three steps, starting with the conversion of nicotinic acid into NAD, utilizing nicotinic acid mononucleotide and nicotinic acid adenine dinucleotide, while the second one is achieved by the action of enzyme NAD+ kinase, which phosphorylates NAD (3, 13, 14)

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