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The selective vulnerability in females led the authors to hypothesize a role for estrogen-linked mechanisms, although this was not tested
IGF-1 LR3 regulates hypertrophy and muscle growth through key pathways like PI3K/Akt/mTOR and PI3K/Akt/GSK3
COMT is involved in the inactivation of catecholamine neurotransmitters such as epinephrine, norepinephrine, and dopamine, but also catecholestrogens and catechol drugs such as the antiParkinsons disease agent LDOPA and the antihypertensive methyldopa (Weinshilboum et al., 1999)
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PMID: 38056998
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