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Drinking less can lower saliva levels and cause a dry mouth feeling
Some individual product SmPCs list musculoskeletal symptoms as uncommon adverse reactions, so frequency varies by specific medication
some respond strongly at lower doses, while others report minimal benefit
separate vials simply remove the stability question and leave the researcher in control
Briefly, a closed testing procedure that operated based on an overall significance level of alpha = 0.05 was allocated to the initial test, which was either a test of non-inferiority for SEM 14 mg compared to active comparators (empagliflozin in PIONEER 2 and sitagliptin in PIONEER 3) or a test of superiority for SEM 14 mg compared to placebo (PIONEER 1, 4, and 8)
