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Combination therapies were shown to have stronger benefits regarding most of the measured parameters [including abnormalities in aspartate aminotransferase (AST) and alanine aminotransferase (ALT) concentrations, markers of systemic inflammation (clear reductions of IL-1 levels), liver inflammation, hepatocellular oxidative stress, hepatic fibrosis and hepatocyte apoptosis] vs

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As someone who has dedicated his career to understanding and treating alcohol use disorder, I recognize the significance of these findings, particularly given the current attention on the adverse health impact of heavy drinking, said Henry Kranzler, Professor of Psychiatry at the University of Pennsylvania Perelman School of Medicine and Principal Investigator of the RECLAIM trial