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Description

Neurotropic viruses, including herpes simplex virus and varicella-zoster virus, can directly invade the ENS via retrograde, hematogenous, or central routes, leading to neuronal dysfunction and gastrointestinal dysmotility

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Despite a relatively short half-life of approximately 30 minutes, the peptide triggers gene expression changes that persist and cascade independently of its continued presence

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The GSSG-dependent oxidation of roGFP2 by fused PfGrx variants is two to three orders of magnitude faster than the oxidation by unfused PfGrx(SSG) variants and more than seven orders of magnitude faster than the uncatalyzed reaction with GSSG (Table 1)

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