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MiRNAs play important roles in basic cellular functions related to development, cellular differentiation, proliferation, apoptosis, cell-cycle control, metabolism and cancer (Iorio and Croce 2012)
Bakirci, S., Dabague, J., Eder, L., McGonagle, D
Phelip JM et al
As we lose this insulation, especially in the first few months, we might find ourselves more sensitive to temperature change, similar to how a thinner blanket provides less warmth than a thick one
These pathological processes are intertwined, forming a vicious cycle of energy depletion-oxidative stress-inflammatory response-cell death-microcirculatory dysfunction, which not only causes AKI but also accelerates the progression of chronic pathologies such as renal interstitial fibrosis, significantly impacting prognosis and clinical outcomes [47, 48]
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