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The screening identified quinoliniums as a promising scaffold, and 5-Amino-1MQ emerged as one of the most active compounds with an IC 50 of approximately 1.2 M under the biochemical assay conditions used
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Bacteriostatic water also can't be used for IV administration without an isotonic admixture, because plain bacteriostatic water without a solute is hypotonic and can cause hemolysis on IV push
NNMT plays a pivotal role in regulating cellular metabolism
Sanitize vials: Remove caps, swab rubber stoppers with 70% isopropyl alcohol, and let air-dry completely
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