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On the safety side, centella and its triterpenes are classified as weak sensitizers, meaning allergic reactions are possible but uncommon
Study location, treatment duration and type of control were detected as sources of heterogeneity following subgroup analysis (Table 2)
Blood work including comprehensive metabolic panel and copper levels provides objective health verification for long-term users
Cells import cystine from the blood, reconvert it to cysteine (likely using ascorbate as cofactor), and from it synthesize GSH
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