Originally developed to regulate insulin resistance in people with type 2 diabetes, semaglutide (also known by certain drug names like Ozempic, Wegovy, and Rybelsus, the oral version) has officially gone mainstream so much so that its sometimes hard to get your hands on the medication
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Depression is not listed as a common or established side effect in the official UK Summary of Product Characteristics for Rybelsus
Patients should verify benefits with their insurance
Zepbound (tirzepatide) is a glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP) receptor agonist that is FDA-approved along with increased physical activity and a reduced-calorie diet for chronic weight management in adults with a starting body mass index (BMI) of: 30 kg/m^2 or higher (obesity) or 27 kg/m^2 or higher (overweight) with at least one weight-related condition such as high cholesterol, high blood pressure (hypertension), type 2 diabetes, heart disease, or obstructive sleep apnea