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Analysis and visualization of PCA and differentially expressed proteomic data Raw data files were processed using the DIA-NN software v.1.8.1 (DIA-NN: neural networks and interference correction enable deep proteome coverage in high throughput) 31 available on GitHub ( DIA-NN was installed in an Apptainer container using the Docker image from Docker Hub ( The analysis was conducted with default parameters

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AF was the most potent inhibitor of TGR, with IC 50 values in the low nanomolar range

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