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When a compound has no completed human trial, there is by definition no safety data in any subgroup no pregnancy data, no hepatic-impairment data, no interaction data with common metabolic or endocrine medications
NHS Blood and Transplant maintains specific medication eligibility criteria that should be consulted directly, as policies regarding newer medications like semaglutide may evolve
semaglutide in direct comparison The clearest head-to-head trial between the two approved molecules for obesity is SURMOUNT-5 (Aronne et al., NEJM 2024, NEJMoa2416394)
Outside of minor side effects like tiredness and nausea, she noticed a difference
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