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The FDA ultimately decides whether to add a substance to the list

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Yes, clinical data shows that subjects taking the formula exhibited a 12.45-fold increase in plasma GLP-1 levels relative to baseline at 90 minutes post-ingestion

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The process is driven in part by genes in what's known as the "mitochondrial respiratory chain complex," a group of enzymes that help convert oxygen, sugar, and proteins into ATP through a process called oxidative phosphorylation