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Other Signs and Symptoms of B12 Deficiency In addition to the above, a vitamin B12 deficiency may cause the following symptoms: Muscle weakness and muscle cramps

Research shows it stimulates the production of collagen types I, II, and III, plus elastin, dermatan sulfate, and decorin all of the structural proteins that keep skin firm

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Patients with a history of severe gastrointestinal disease, particularly those with inflammatory bowel disease, severe gastroesophageal reflux disease, or history of pancreatitis, require careful evaluation before considering this therapy

Most patients experience identical outcomes on either formulation