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At the end of 1 year semaglutide dose was reduced to 3 mg and then continued till 18 months
While other regions show growth potential, Western Europe remains the largest and most significant market
Participants also showed reduced waist circumference, blood pressure, fasting blood glucose, and insulin levels, along with nearly complete elimination of liver fat in a prior MASLD substudy
Like semaglutide, the starting dose of 2.5 mg is not the therapeutic dose
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This is partly because the body's weight set point defends against the lower weight, and partly because GLP-1 receptors in the brain that were being continuously stimulated are no longer activated
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