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NICE guidelines recommend GLP-1 receptor agonists as part of the treatment algorithm for type 2 diabetes when metformin and other oral agents have not achieved adequate glycaemic control

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Additional information Peer review information Nature Reviews Endocrinology thanks G

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FDA approval for evolocumab covers three indications: adults with heterozygous familial hypercholesterolemia (HeFH), adults or pediatric patients aged 13 and older with homozygous familial hypercholesterolemia (HoFH), and adults with established atherosclerotic cardiovascular disease (ASCVD) who need additional LDL-C lowering beyond maximally tolerated statin therapy [1]

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Data reliability and reproducibility were confirmed according to previously described protocols described (de Castro et al

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The approval covers oral semaglutide 25 mg for adults with a body mass index of at least 30, or at least 27 with one weight-related health condition, alongside diet and exercise

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