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Severe hypersensitivity reactions, including anaphylaxis, have been reported, and the medication should be discontinued if this occurs

While taking steroid medications, doctors may recommend that people with diabetes consider: checking blood glucose levels more often than usual potentially four or more times per day increasing the dosage of insulin or oral medication, depending on blood sugar levels and if a doctor advises it monitoring urine or blood ketones consulting a doctor immediately if blood sugar levels rise too high while taking steroids and the insulin or oral medication dose is insufficient to bring the levels down carrying glucose tablets, juice, or candy at all times in case blood sugar levels drop suddenly As people gradually reduce their steroid dosage, they also need to reduce the equivalent dosage of insulin or oral medication until it returns to the original dosage

As a pharmacological agent, papaverine is not exempt from adverse effects including endothelium damage, epileptic seizures, transient neurological dysfunction, and hemodynamic changes, among others (Dipp et al., 2001

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"Hydralazine and magnesium valproate as epigenetic treatment for myelodysplastic syndrome