The discontinuation rates due to adverse events, which were comparable to placebo, suggest that the transition to oral orforglipron is generally well-tolerated by patients already acclimated to incretin therapy
Diabetes Care 42(12):22622271 Funding This research was supported by the Industrial Strategic Technology Development Program (20018218, Development of oral drug formulation technology and process technology based on continuous process and RS-2023-00230559, Development of integrated solution technology for QbD-based continuous process) funded by the Ministry of Trade, Industry & Energy (MOTIE, Korea)
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The risk of low blood sugar (hypoglycemia) remains low unless combined with other diabetes medications like insulin