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Limitations of current therapeutic strategies Current clinical management of RIRI primarily relies on antioxidant agentssuch as N-acetylcysteine and vitamins E/Canti-inflammatory drugs including non-steroidal anti-inflammatory agents (NSAIDs), and nephroprotective compounds like amino acids and indomethacin, often supplemented by supportive measures such as fluid resuscitation and extracorporeal blood purification
Obesity medications may counter the effects of metabolic adaptation and prevent weight regain
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In one trial, small weekly doses of CJC-1295 significantly increased both peak and baseline GH levels and boosted IGF-1 by 1.53x for 911 days
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