Depending on the patients goals and needs, it can last from 3 to 12 months
CrossRef Bile acid metabolism and signaling: Emerging pharmacological targets of dietary polyphenols Kevin M
Immune-related transcripts were also elevated in 17-week-old mice, including antigen presentation genes linked to MHC class I ( H2-K1 , H2-Q6 , B2m ) and class II ( H2-Ab1 , H2-Eb1 , Cd74 ), as well as T cell chemoattractants ( Cxcl10 , Cxcl9 , Ccl5 )
It is administered once weekly, similar to injectable semaglutide, and offers similar benefits in terms of glycemic control and weight loss
Labeling update (2026): The FDA recently removed suicidal behavior and ideation language from the labeling of certain GLP-1 medicines used for chronic weight management, following a comprehensive safety review that found no evidence of increased risk