How Many People Are on GLP-1 Drugs and Where It's Headed GLP-1 receptor agonists originally developed to manage type 2 diabetes became a mainstream weight-loss category after Ozempic's consumer breakthrough in 2023
The numbers below assume the standard research-planning band of about 250 mcg twice daily from 10 mg vials reconstituted with 2 mL bacteriostatic water
Diabetol Metab Syndr 15(1):161 Ingold I, Berndt C, Schmitt S, Doll S, Poschmann G, Buday K, Roveri A, Peng X, Porto Freitas F, Seibt T et al (2018) Selenium utilization by GPX4 is required to prevent hydroperoxide-induced ferroptosis
"About 70% of the weight loss is fatty cells and about 30% is muscle cells
Peer review Peer review information Nature Aging thanks Valter Longo and the other, anonymous, reviewer(s) for their contribution to the peer review of this work