bpc-157 spinal cord injury Novel Therapeutic Effects in Rat Injuries: Recovery of the Definitive and Early Spinal Cord by the Administration of Pentadecapeptide BPC 157 Therapy After a major spinal injury,

Reprinted in commentary: Current Issues in Molecular Biology

J Leukoc Biol

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(4) Blood Pressure (3) In blood pressure studies, compared with l-arginine, pentadecapeptide BPC 157 (without effect on basal normal values) had both a mimicking effect (impaired l-NAME-blood pressure increase, when applied prophylactically and decreased already raised l-NAME values, given at the time of the maximal l-NAME-blood pressure increase (i.e., 10 min after l-NAME)) and preventive activity (l-arginine-induced moderate blood pressure decrease was prevented by BPC 157 pretreatment)

No change at a tolerated dose can indicate limited response, but it does not support faster-than-label escalation