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Beyond weight
The most common adverse effects of tirzepatide at weight management doses include gastrointestinal symptoms such as nausea (24-43% of patients), diarrhea (18-31%), vomiting (8-24%), constipation (16-24%), and abdominal pain (10-20%), according to the FDA label
Continuous positive airway pressure (CPAP) remains a standard treatment, but adherence is a persistent problem, as reported by BNN Bloomberg
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GLP-1 anorexia beyond the direct hypothalamus/hindbrain action Central or peripheral GLP-1 injection reduces food intake in rodents and man (Turton et al., 1996
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