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These modifications serve to make the molecule more resistant to degradation by dipeptidyl peptidase-4 (DPP-4) enzymes, which would otherwise break down the peptide structure

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However, unlike GIPR, GLP-1R are present in several other tissues such as peripheral nervous system, lung and heart (Figure 2) [19]

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Ankles, Achilles tendons, wrists, hands, and feet have almost no subcutaneous fat, and there is no version of this protocol where you inject into one of them